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The Cannabis Review® | Effects

Cannabis has been shown to have many beneficial effects on users. The Cannabis Review® | Effects is a collection of scientific studies that identifies the molecules, found in cannabis, that have specific effects on users, the magnitude of that effect, and the amount of molecule used in the study.

Grade

This is the measurement of the nature and methodology of the scientific study.

Double-blind, placebo controlled clinical study
Open clinical trial study; no control group and no blinded clinical trial
Non-human subject research on isolated cannabis compounds
Non-human subject research on cannabis compound in a mixture

Magnitude of Effect

This identifies how effective the biological activity of the cannabinoid was treating the condition.

majorBiological activity has a major effect on the condition
moderateBiological activity has a moderate effect on the condition
minorBiological activity has a minor effect on the condition

Primary Studies

The following scientific studies establish the potential effectiveness for treating specific conditions using molecules found in cannabis. The study names link to the full studies; click to view.

EffectMagnitudeCannabinoid/ TerpeneCondition treatedAmount usedStudyGrade
AnalgesicmajorBorneolPainN/AA clinical and mechanistic study of topical borneol‐induced analgesia
THC (Tetrahydrocannabinol)Neuropathic Pain25mgSmoked cannabis for chronic neuropathic pain: a randomized controlled trial
minorMyrceneHyperalgesiaN/AMyrcene mimics the peripheral analgesic activity of lemongrass tea.
THC (Tetrahydrocannabinol)Multiple sclerosis10mgDoes the cannabinoid dronabinol reduce central pain in multiple sclerosis? Randomised double blind placebo controlled crossover trial.
Pain5mgLack of analgesic efficacy of oral delta-9-tetrahydrocannabinol in postoperative pain
moderateCBD (Cannabidiol)Central neuropathic pain25mg/mLOromucosal Δ9-tetrahydrocannabinol/cannabidiol for neuropathic pain associated with multiple sclerosis: An uncontrolled, open-label, 2-year extension trial
Multiple sclerosis2.5mgRandomized, controlled trial of cannabis-based medicine in central pain in multiple sclerosis
2-10 inhalationsA double-blind, randomized, placebo-controlled, parallel-group study of THC/CBD oromucosal spray in combination with the existing treatment regimen, in the relief of central neuropathic pain in patients with multiple sclerosis
2-10 inhalationsA double-blind, randomized, placebo-controlled, parallel-group study of THC/CBD oromucosal spray in combination with the existing treatment regimen, in the relief of central neuropathic pain in patients with multiple sclerosis
Pain2.5mgInitial experiences with medicinal extracts of cannabis for chronic pain: results from 34 ‘N of 1’ studies

Secondary Materials

The following are study reviews and other materials of note

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